Abstract
Asthma and chronic bronchitis are common chronic respiratory diseases characterized by airway inflammation, bronchial hyperresponsiveness, and airflow obstruction, leading to recurrent respiratory symptoms, exacerbations, and impaired quality of life for affected individuals. This review article provides a comprehensive overview of asthma and chronic bronchitis, focusing on their epidemiology, etiology, pathophysiology, clinical manifestations, diagnosis, management, treatment guidelines, emerging therapies, and future directions in respiratory medicine. Key topics covered include the prevalence, risk factors, and burden of asthma and chronic bronchitis, the underlying mechanisms contributing to disease development and progression, diagnostic approaches, including patient history, physical examination, and objective testing, and management strategies encompassing patient education, environmental control, medication therapy, and non-pharmacological interventions. Treatment guidelines developed by international organizations such as the Global Initiative for Asthma (GINA) and the Global Initiative for Chronic Obstructive Lung Disease (GOLD) are discussed, along with emerging therapies, including biologic agents, precision medicine approaches, digital health technologies, and patient-centered care models. Future directions in respiratory medicine are explored, highlighting the potential for continued advancements in research, technology, and clinical practice to improve treatment outcomes, enhance patient care, and reduce the global burden of asthma and chronic bronchitis.