• Nikita Chauhan
• Swati Jayswal

Use of medicinal plants with anti-microbial characteristics seems sensible and can be used as alternative approach to combat with microbial resistance to antibiotics and the prevalence of adverse effects. The present study- was designed to evaluate the phytochemicals of Tinospora cordifolia (Giloy), Glycorrhiza glabra (Mulethi), Cinnamomum verum (Cinnamon), Zingiber officinale (Ginger) extracts and their antibacterial potency against laboratory Salmonella paratyphi A, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa. The qualitative analysis is very essential to identify the phytochemical constituent present in plants. The medicinal value of plants is due to the presence of particular bioactive constituents which can be easily accessed by standard methods. Nowadays, researchers are in search of some novel antimicrobial molecules which have a broad spectrum of activity against both Gram-negative and Gram-positive bacteria without having many or any side effects. Agar Well diffusion method is used to test antimicrobial activity of all plant extract prepared in different solvents methanol, ethanol, chloroform, and distilled water against pathogenic bacteria.Apart from these, each plant extract was mixed in equal proportion and same procedure was followed to study their synergistic effect.To overcome such problems, synergistic approach can be applied to reduce the dose of antibiotics and to enhance the effectiveness within the combination of different plant extracts. Different nanoparticles will be synthesized via biological to study their synergistic effects with the combination of different plant extract and antibiotics. This review is emphasis on bio-efficacy of selected plants which works as strong pillar to the upcoming researches.

Phytochemical; Synergistic effect; Antibiotic; Antibacterial, Plant extract

"BIOEFFICACY AND SYNERGISTIC ACTIVITY OF MEDICINAL PLANTS AGAINST SELECTED MICROORGANISMS- A REVIEW", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 5, page no.a406-a410, May-2024, Available :http://www.jetir.org/papers/JETIR2405048.pdf

"BIOEFFICACY AND SYNERGISTIC ACTIVITY OF MEDICINAL PLANTS AGAINST SELECTED MICROORGANISMS- A REVIEW", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 5, page no. ppa406-a410, May-2024, Available at : http://www.jetir.org/papers/JETIR2405048.pdf