• RUSHIKESH KAKASAHEB POKALE
• RUCHITA PAWAR
• SANJAY TAVALE
• PRATIKSHA BIRANGAL
• Dr. S.Z.CHEMATE

Self- emulsifying drug delivery system has received attention for its capacity to enhance the solubility and bioavailability of drugs that are poorly water-soluble drugs. Self-emulsifying drug delivery systems are isotropic mixtures of drug, lipids and surfactants, usually with one or more hydrophilic cosolvents or co-emulsifier with droplet size ranging from few nanometers to several micrometers. SEDDS belong to lipid-based formulations. Lipid formulations can be oils, surfactant dispersions, emulsions, SEDDS, solid lipid nanoparticles and liposomes. SEEDS are ranging in size from approximately 100 nm (SEDDS) to less than 50 nm for self-micro-emulsifying drug delivery systems (SMEDDS), on dilution with physiological fluid. This article provides an overview of self-emulsifying drug delivery system and their applications, as well as their ability to resist first-pass metabolism.

Self-emulsifying drug delivery system, needs, mechanism, applications, future aspects.

"Self-emulsifying drug delivery system: Approach to avoid first pass metabolism", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 5, page no.a780-a786, May-2024, Available :http://www.jetir.org/papers/JETIR2405092.pdf

"Self-emulsifying drug delivery system: Approach to avoid first pass metabolism", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 5, page no. ppa780-a786, May-2024, Available at : http://www.jetir.org/papers/JETIR2405092.pdf