• K.Sri Chaya Reddy
• Morupoju.sushma
• B.Naga jyothi

The purpose of present study was to develop optimized and controlled release formulation for oral drug delivery of Telmisartan in order to ensure maximum controlled drug release. Telmisartan is an angiotensin 2 receptor antagonist (angiotensin receptor blocker) used in the management of hypertension. In this preparation the natural disintegrants are Banana powder, pectin from orange peel, and mucilage from isapgol seeds are used.The present research aims to enhance the dissolution profile of telmisartan through formulation of its fast disintegrating tablets using a super natural disintegration.Matrix tablets are an interesting option and new break through when developing an oral controlled release drug delivery system. Various controlled release drug delivery system have different mechanism to control the drug release rate such as osmotic pump, ion exchange resin and matrix systems.All the prepared formulations were evaluated for thickness, weight variation, hardness, friability, drug content and in vitro dispersion time and dissolution profile are found satisfactory.

Controlled release, matrix tablets, telmisartan, natural polymers, superdisintegrants

"FORMULATION AND INVITRO CHARACTERISATION STUDIES OF CONTROLLED RELEASE TABLETS OF TELMISARTAN BY USING NATURAL POLYMERS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 5, page no.e100-e106, May-2024, Available :http://www.jetir.org/papers/JETIR2405409.pdf

"FORMULATION AND INVITRO CHARACTERISATION STUDIES OF CONTROLLED RELEASE TABLETS OF TELMISARTAN BY USING NATURAL POLYMERS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 5, page no. ppe100-e106, May-2024, Available at : http://www.jetir.org/papers/JETIR2405409.pdf