• Amrata Sanjay Mantri
• Vaishnavi Gennd

Medicated chewing gum, a soft, cohesive enjoyable confectionery product loaded with bioactive compounds are chewed to release the bioactive for healing targeted parts. Currently, the production of chewing gum in the global chewing gum market is rapidly increasing from USD 25 billion to an estimated USD 37 billion by the year 2023. The application of chewing gum in drug delivery system has increased compared to pharmaceutical pre-dosage form. However, gum bases are thrown away after chewing which generates non-biodegradable waste causing harmful effects to the environment as well as living organisms. In this research the comparative study of three natural gum base is done and its biodegradability is compared with the synthetic gum base. The gum bases used for this research is Chicle (extracted from Sapodilla Monikara tree), Prolamin (extracted from Triticum Aestivum flour) and Zein (extracted from corn). All bases were evaluated for the swelling index, water retention capacity, loss on drying and antimicrobial activity. Thus, this study suggested that the prolamin base showed good results as compared to others and was biodegradable within 2 weeks.

medicted chewing gum, biodegradable, chicle, prolamin, zein, gum base

"Comparative study on gum natural gum bases used for medicated chewing gum", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 5, page no.i181-i189, May-2024, Available :http://www.jetir.org/papers/JETIR2405824.pdf

"Comparative study on gum natural gum bases used for medicated chewing gum", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 5, page no. ppi181-i189, May-2024, Available at : http://www.jetir.org/papers/JETIR2405824.pdf