• Jyoti Kumari
• Dr.Akhlesh Kumar Singhai
• Ms.Steffi Thomas
• Dr.Akhlesh Singhai

Herbosomes, a novel lipid-based drug delivery system, were formulated using Adenostemma lavenia extract to enhance its therapeutic potential. The study involved the preparation of herbosomes by the thin-film hydration method and their subsequent evaluation for various parameters. Physicochemical characterization, including particle size, zeta potential, entrapment efficiency, and morphology, was performed to assess the quality of the formulated herbosomes. The resulting formulations were found to be porous, smooth, and spherical. The particle size and zeta potential were determined using the Malvern Zeta sizer, with the average particle size for formulations F1 and F5 being 158.8 nm to 551.3 nm. The antimicrobial activity of Adenostemma lavenia herbosomes was evaluated against microbial strain using standard methods. As the concentration of the herbosomes increases, there is a noticeable increase in the zone of inhibition, indicating enhanced antimicrobial activity against E. Coli.The results indicated that the formulated herbosomes exhibited promising antimicrobial activity compared to the free extract. This study demonstrates the potential of Adenostemma lavenia herbosomes as effective antimicrobial agents, suggesting their potential application in pharmaceutical formulations.

"Formulation and evaluation of herbosomes of Adenostemma levenia and study it's anti -microbial activity ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 5, page no.i202-i210, May-2024, Available :http://www.jetir.org/papers/JETIR2405827.pdf

"Formulation and evaluation of herbosomes of Adenostemma levenia and study it's anti -microbial activity ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 5, page no. ppi202-i210, May-2024, Available at : http://www.jetir.org/papers/JETIR2405827.pdf