• SHINTU NAYARASSERY
• JYOTHILEKSHMI S
• LIJY JACOB
• MANEESHA CR
• SHERIN ANNIE ABRAHAM

Tropical India and Peninsular India is famous for its rich medicinal plant wealth and the tradition of indigenous system of therapy, Ayurveda. Plants have been used for the cure of various diseases in Ayurveda and is extensively used by the elder generation. The present study is to evaluate the phytochemical composition, and to screen for the in vitro antioxidant and cytotoxicity effects of leaves of Cucurbita maxima,a potential plant which is culturally and medicinally significant to the people of Kerala.Among all the extracts methanolic leaf extract of Cucurbita maxima showed higher phenolic and flavonoid content and significant DPPH scavenging activity. The in vitro cytotoxicity was tested against Hep G2 (hepatocellular liver carcinoma) in which methanolic extract of Cucurbita maxima showed an IC50 108.72 µg/ml at 48hr.Our study confirmed that theleaves of Cucurbita maxima has better antioxidant and anticancer properties and hence consuming of its leaves as food will definitely rejuvenate our body.

Phytochemical analysis, Antioxidant, Cytotoxicity, Traditional medicinal plants.

"In Vitro Antioxidant And Cytotoxic Efficacy Of Cucurbita maxima: From The Medicinal Plant Wealth Of Peninsular India", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.640-645, May-2019, Available :http://www.jetir.org/papers/JETIR1905896.pdf

"In Vitro Antioxidant And Cytotoxic Efficacy Of Cucurbita maxima: From The Medicinal Plant Wealth Of Peninsular India", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp640-645, May-2019, Available at : http://www.jetir.org/papers/JETIR1905896.pdf