• Masese Osoro Brian
• S. Selvi

The aim of this study is to investigate the cytotoxic effect the ethanolic leaf and bark extracts of Ceiba pentandra. In this study phytochemical extraction has been done by cold maceration method using four different types of solvents of increasing polarity (petroleum ether, ethyl acetate, acetone, and ethanol). In the phytochemical analysis the ethanolic leaf and bark extracts of Ceiba pentandra, showed the presence of more phytochemicals when compared to other solvent extracts. MTT assay was used to determine the anticancer potential of the selected plant extracts. The ethanol bark extract possessed a higher inhibitory effect against colon cancer cell line, compared to ethanol leaf extract and the IC50 values were 74.22% and 194.52% respectively. In our study observation, ethanol bark extract showed the highest inhibitory effect on colon cancer cell line when compared to the ethanol leaf extract.

Ceiba pentandra; Cytotoxicity; MTT assay; HCT-116 cancer cells

"Anticancer and Cytotoxic Potential of Ethanolic extract of Ceiba pentandra L. leaf and bark on HCT-116 cell lines.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.49-53, May-2019, Available :http://www.jetir.org/papers/JETIR1905B08.pdf

"Anticancer and Cytotoxic Potential of Ethanolic extract of Ceiba pentandra L. leaf and bark on HCT-116 cell lines.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp49-53, May-2019, Available at : http://www.jetir.org/papers/JETIR1905B08.pdf