• Snehal Jagtap
• Dr. Abhijeet Kulkarni
• Pallavi Kandalkar

The Fast Dissolving / Disintegrating is a novel drug delivery system .Fast-dissolving / Disintegrating oral drug delivery systems are the solid oral dosage forms, which get disintegrate or dissolve within 1 min when placed in the oral cavity without drinking water or chewing. It enhances the safety and efficacy of the drug molecule. It enhance the fast onset o set of action which improve the bioavailability by avoiding the first pass metabolism and enzymatic degradation in GI tract. These dosage form is convenience to the special category patients such as Pediatrics, geriatrics and bedridden patients who having difficulty in Swallowing the conventional dosage form. These system consist of Thin Film or Wafer, which is placed on the patient’s tongue or oral mucosal tissue, it instantly get wet by the saliva and it rapidly get hydrates and adhere on the site of application. It is get disintegrates and dissolve rapidly and release the medication to the mucosal absorption. Recently the Fast Dissolving Film or Wafer are gaining the interest as alternative to the fast dissolving tablets which definitely eliminates the fear of patients of chocking. These formulation are formulated by using the polymers, plasticizers, sweeteners, flavours and colors. These are prepared by using the various methods like casting, extrusion etc. the film/ wafer is evaluated by using various evaluation parameters like disintegration time, dissolution time, thickness, etc.

Fast Dissolving Oral Wafer, Polymer, Solvent Casting Method, Bioavailability Enhancement.

"A Novel Venture in Oral Formulation: Wafer", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 4, page no.345-359, April 2020, Available :http://www.jetir.org/papers/JETIR2004541.pdf

"A Novel Venture in Oral Formulation: Wafer", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 4, page no. pp345-359, April 2020, Available at : http://www.jetir.org/papers/JETIR2004541.pdf