• MURUGESWARI K
• Dr. Mohamed Shiek Arabath S A
• Pradeep M
• Muthudharshini A
• Nathivarshini M,Padma S,Santhana pandi N

Abstract Objective: A hydroalcoholic extract of Klenia grandiflora leaves was evaluated for its anti-microbial and anti-oxidant properties. Most areas with a warm climate have a large variety of Klenia grandiflora, which are popular ornamental plants. Methods: A hydroalcoholic extract of Klenia grandiflora (leaves) was tested for anti-microbial activity by observing the Minimum Inhibitory Concentration zone of inhibition against both gram- positive and gram-negative bacterial strains, including Staphylococcus aureus, Bacillus substilis, and E. coli. Agar cup plates were used to study antibacterial activity, and hydrogen peroxide free radical scavenging was used to assess antioxidant activity. Results: Inhibitory zones were observed against gram negative as well as gram positive bacteria by the hydroalcoholic extract of Klenia grandiflora. The anti-microbial effects of Gentamicin standard showed inhibitory effect on E. coli, Staphylococcus aureus and Bacillus substilis extremely low concentration. Klenia grandiflora hydroalcoholic extracts were found to inhibit H2O2 scavenging activity by a significant amount compared to ascorbic acid in the study. Several antimicrobial and antioxidant activities of the plant were found in this study. Conclusion: Discovering metabolites from Klenia grandiflora may lead to the development of anti-biotics and anti-oxidants. It may be possible to identify antimicrobial and antioxidant metabolites in Klenia grandiflora by exploring its potential.

Klenia grandiflora, Anti-oxidant, Anti-microbial, Extracts, Drugs

"PHARMACOGNOSTICAL, PHYTOCHEMICAL SCREENING, INVITRO ANTI-OXIDANT AND ANTI-BACTERIAL ACTIVITY OF Klenia grandiflora", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 6, page no.i299-i310, June-2023, Available :http://www.jetir.org/papers/JETIR2306834.pdf

"PHARMACOGNOSTICAL, PHYTOCHEMICAL SCREENING, INVITRO ANTI-OXIDANT AND ANTI-BACTERIAL ACTIVITY OF Klenia grandiflora", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 6, page no. ppi299-i310, June-2023, Available at : http://www.jetir.org/papers/JETIR2306834.pdf