• Olagboye, Sulaiman Adeoye
• Adebawore, Adefusisoye Adegalu
• Akinyeye, Richard Odunayo
• Akinnawo, Ayobami Sunday

The newly synthesized metal chelate of sodium barbitone with the Ni (II) and Mn (II) ions was examined and characterized by elemental analysis, colors and melting points/thermal decomposition, and the Infra-red (IR), UV-visible spectroscopic methods to predict the sites for metals coordination. The antimicrobial studies of sodium barbitone ligand (free ligand) together with its metal chelates serve as references for the following antibacterial organisms (Salmonella typhi, Ralstonia solanacearum, Streptococcus faecalis, Erwinia carotovora, and Pseudomonas glycinea) and the following antifungal organisms (Serpula lacrymans, Epidermophyton floccosum, and Trichophyton verrucosum). The activity data show that the metals chelate have pronounced activity with a promising biological activity compared to sodium barbitone parent-free ligand against bacteria and fungi species.

Spectroscopic techniques; anti-microbial activities; barbitone; metal ions.

"Synthesis, characterization and anti-microbial activities of Ni (II) and Mn (ii) of barbitone in water medium", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 7, page no.j47-j58, July-2023, Available :http://www.jetir.org/papers/JETIR2307907.pdf

"Synthesis, characterization and anti-microbial activities of Ni (II) and Mn (ii) of barbitone in water medium", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 7, page no. ppj47-j58, July-2023, Available at : http://www.jetir.org/papers/JETIR2307907.pdf