• Rajkumar G. Momle
• Suresh G. Vedpathak
• Gopal K. Kakade

Cu (II) complexes were synthesized from novel Schiff bases prepared by reacting 5-methyl-1H-tetrazol-1-yl substituted anilines with salicyaldehyde and 5-bromo-2-hydroxybenzaldehyde in hot alcoholic solution. The complexes were subjected for their antibacterial screening where the activity of Cu (II) complexes 4a and 4b against Salmonella typhi with MIC 26 mm were found more potent than standard drug tetracycline (21 mm) while other complexes have shown comparable antibacterial activity at the same concentration. Antifungal activity of the ligands has enhanced on complexation with Cu (II) metal where complexes 4a and 4b shows potent antifungal activity against S. cerevisiae and A. niger than the other complexes.

Antibacterial activity, Antifungal activity, Cu (II) complexes, Schiff bases, Tetrazole.

"Synthesis and antimicrobial activity of Cu (II) complexes of some novel 4-5-methyl-1H-tetrazol-1-yl Schiff base ligands", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 11, page no.c341-c343, November-2023, Available :http://www.jetir.org/papers/JETIR2311247.pdf

"Synthesis and antimicrobial activity of Cu (II) complexes of some novel 4-5-methyl-1H-tetrazol-1-yl Schiff base ligands", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 11, page no. ppc341-c343, November-2023, Available at : http://www.jetir.org/papers/JETIR2311247.pdf