• Aruna mallaram
• Sreenivas Vasam
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This study explores the synthesis and antimicrobial evaluation of a series of N-(4-(1,2-dihydrophthalazin-1-yl) phenyl) amides as potential agents against Xanthomonas campestris and Escherichia coli. These compounds were synthesized efficiently from readily available phthalic anhydride and subjected to thorough characterization using various spectroscopic techniques including 1H NMR, 13C NMR, IR, and LCMS. Through these techniques, the structures of the synthesized compounds were confirmed with precision. In vitro, antimicrobial assays were conducted to assess the efficacy of the synthesized compounds against Xanthomonas campestris and Escherichia coli. The results revealed promising antimicrobial activity of the compounds against both bacterial strains. This indicates the potential of N-(4-(1,2-dihydrophthalazin-1-yl) phenyl) amides as effective antimicrobial agents. Xanthomonas campestris and Escherichia coli are significant bacterial pathogens known to cause various diseases in plants and humans, respectively. Therefore, the identification of compounds with potent antimicrobial activity against these pathogens holds considerable importance for agricultural and medical applications. Overall, this research underscores the potential of N-(4-(1,2-dihydrophthalazin-1-yl) phenyl) amides as promising antimicrobial agents targeting Xanthomonas campestris and Escherichia coli. Further studies could focus on elucidating the mechanism of action of these compounds and exploring their potential for practical applications in agriculture and medicine.

N-(4-(1,2-dihydrophthalazin-1-yl) phenyl) amides, Synthesis, Antimicrobial evaluation, Xanthomonas campestris, Escherichia coli, Spectroscopic techniques, In vitro assays, Phthalic anhydride, and Antibacterial agents.

"Synthesis and Antimicrobial Evaluation of N-(4-(1,2-Dihydrophthalazin-1-yl) phenyl) amides as Potent Agents against Xanthomonas campestris, and Escherichia coli", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 4, page no.j426-j432, April-2024, Available :http://www.jetir.org/papers/JETIR2404957.pdf

"Synthesis and Antimicrobial Evaluation of N-(4-(1,2-Dihydrophthalazin-1-yl) phenyl) amides as Potent Agents against Xanthomonas campestris, and Escherichia coli", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 4, page no. ppj426-j432, April-2024, Available at : http://www.jetir.org/papers/JETIR2404957.pdf