• Dr. Sajja Ravindra Babu
• B.Siddhartha
• B.Divya
• B.Sowmya

Objective: To evaluate efficacy and tolerability of antipsychotic drugs in tertiary care hospital. Methodology: This is a hospital-based prospective observational study conducted in the inpatient and outpatient psychiatry departments over 6 months with patients who met the inclusion criteria. The patients have been prescribed Olanzapine, Risperidone, Aripiprazole, and Haloperidol. The symptoms of the patients were assessed by using the Positive and Negative Syndrome Scale (PANSS). To estimate the severity of illness Clinical Global Impression Scale for Severity of Illness is used. The improvement of the condition is evaluated by Clinical Global Impression-Improvement Scale. Results: A total of 105 patients were included in the study. Among them, females and males are equally affected the average age of the subjects was 36.62 and 37.14. 29-39 age range of the people were most affected. There is a much reduction in the PANSS, CGI-S, and CGI-I mean and standard deviation from baseline follow-up after 2 months. Conclusion: The findings of the study revealed that people in rural areas, uneducated, unemployed, and divorced were higher in number. Among the four medications used by the patients, Haloperidol showed efficacy and tolerability among the 105 patients.

Antipsychotics, Schizophrenia, Tolerability, Olanzapine

"Appraisal of Efficacy and Tolerability of Antipsychotic Drugs in Tertiary Care Hospital ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 6, page no.e189-e196, June-2024, Available :http://www.jetir.org/papers/JETIR2406429.pdf

"Appraisal of Efficacy and Tolerability of Antipsychotic Drugs in Tertiary Care Hospital ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 6, page no. ppe189-e196, June-2024, Available at : http://www.jetir.org/papers/JETIR2406429.pdf