• Neha R. Madavi
• Amit R. Jaiswal

The purpose of the current study is formulated and evaluates herbal anti-inflammatory gel of fruit extract of Lagenaria Siceraria for topical application anti-inflammatory activity. Using the methanolic fruit extract lagenaria siceraria. Gelling agent used in this study was 1% w/w concentration of carbopol- 934. The in vivo studies were conducted on Sprague dawley rats of either sex (120-200 gm). Change in edema volume of the rat hind paw was measured. The anti-inflammatory effect produced after topical administration of herbal gel formulation on Carrageenan-induced rat paw edema exhibited a high degree of reproducibility. The initial physicochemical parameters of formulations (F1, F2, F3) i.e. pH, viscosity, spreadability, homogeniety, washability and stability were also examined. The all prepared formulations F1 batch i.e., 5% of Lagenaria Siceraria herbal gel shows anti-inflammatory activity carrageenan-induced rat edema. The preparation remained stable under typical storage conditions and caused no skin irritation.

Herbal Gel, Inflammation, Lagenaria Siceraria Fruit Extract, Cucurbitacea, Carrageenan, Methanolic Extract, Evaluation

"TO FORMULATE AND EVALUATE HERBAL ANTI-INFLAMMATORY GEL OF FRUIT EXTRACT OF LAGENARIA SICERARIA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 6, page no.h450-h459, June-2024, Available :http://www.jetir.org/papers/JETIR2406750.pdf

"TO FORMULATE AND EVALUATE HERBAL ANTI-INFLAMMATORY GEL OF FRUIT EXTRACT OF LAGENARIA SICERARIA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 6, page no. pph450-h459, June-2024, Available at : http://www.jetir.org/papers/JETIR2406750.pdf