• Aithal S.V
• Jadhav V.K.

Various extracts of solvent of Tinospora cordifolia (family- Menispermaceae) leaves such as hexane, chloroform, dichloromethane, ethyl acetate, methanol and aqueous were evaluated for their phytochemical and antifungal activity against selected fungal sps.like Aspergillus niger, Aspergillus fumigatus, Candida albicans, Saccharomyces cerevisiae and Microsporum gypseum by paper disc diffusion method. The activities of the samples were compared with that of standard antibiotics ‘Griseofulvin.’ Phyto-chemical screening of Tinospora cordifolia leaf extract in five different solvents showed the presence of important Phyto-constituents like phenols, alkaloids, flavonoids, tannins and saponins. In antifungal assay, all the organisms respond to the plant extract but inhibitory zone developed. The chloroform extract showed a higher activity than other extracts. The methanolic extract of T. cordifolia showed higher activity against A. fumigatus and A. niger followed by, Candida albicans, Saccharomyces cerevisiae and Microsporum gypseum the methanolic extract of T. cordifolia showed maximum zone of inhibition against A. fumigatus. The ethyl acetate extract of T. cordifolia exhibited high activity against A. niger and A. fumigatus followed by methanol, chloroform, hexane, and aqueous extracts. The results revealed that the antimicrobial activity exhibited by T. cordifolia, chloroform and aqueous extract noted to be most effective than other solvents.

Tinospora cordifolia, leaves extracts, phytochemical Screening, antifungal activity

"Antifungal activity and Phytochemical screening of Tinospora cordifolia", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 4, page no.650-654, April-2023, Available :http://www.jetir.org/papers/JETIRFW06087.pdf

"Antifungal activity and Phytochemical screening of Tinospora cordifolia", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 4, page no. pp650-654, April-2023, Available at : http://www.jetir.org/papers/JETIRFW06087.pdf