• Ankita Salgaonkar
• Hitesh Gurav

Increase in antibiotic resistance and nosocomial infections are problems that have been reported for many years around the world causing economical burden and prolonged treatment. The majority of infections are caused by multidrug-resistant bacteria coming from the hospital-acquired environment. This study aims to eliminate or decrease their antibiotic resistance and to eliminate their Virulence factors, By using traditional medicine in a form of fermented kwatha. As fermentation is a process of preparing formulations wherein therapeutic attributes of a group of ingredients are extracted out of either freshly extracted juice of plants (Asava) or kwatha, a decoction prepared in water (Arishta) with the help of biochemical or microbial fermentation and anaerobic respiration into the liquid. In this study fermented kwath was prepared by using the coarse powder of a plant part in a form of a decoction. Fermentation was carried out for 1 month with decoction and with jaggery and dry dates (kharik) as a source of sugar. The Woodfordia fruticose (Dhataki) flowers and Baker’s yeast as fermenting agents. During fermentation self generated alcohol will help to extract phytochemicals from plants which will helps to eliminate virulence factor and will show antimicrobial effect on bacterial isolates. Self generated alcohol also contributes during quicker absorption and preservation. Dry dates shown to give less amount of residual sugar, and will be beneficial for diabetic patient .

Nosocomial infections, medicinal plants, Multidrug resistance, fermentation, fermented kwatha (Arishta), antimicrobial effect.

"PREPARATION OF HERBAL FERMENTED KWATH AND STUDY ITS EFFECT ON NOSOCOMIAL PATHOGENS CAUSING RESPIRATORY TRACT INFECTIONS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 6, page no.47-55, June-2023, Available :http://www.jetir.org/papers/JETIRFY06007.pdf

"PREPARATION OF HERBAL FERMENTED KWATH AND STUDY ITS EFFECT ON NOSOCOMIAL PATHOGENS CAUSING RESPIRATORY TRACT INFECTIONS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 6, page no. pp47-55, June-2023, Available at : http://www.jetir.org/papers/JETIRFY06007.pdf